Abstract Background Neoadjuvant therapy improves recurrence-free survival (RFS) in resectable stage III cutaneous melanoma.However, accurately predicting individual recurrence risk remains a significant challenge.We investigated circulating tumour DNA Supplements (ctDNA) as a biomarker for recurrence in measurable stage IIIB/C melanoma patients und
Animal models should display important characteristics of the human disease.Sheep have been considered particularly useful to study allergic airway responses to common natural antigens causing human asthma.A rationale of this study was to establish a model of ovine precision-cut lung slices (PCLS) for the in vitro measurement of airway responses in
Forensic fire debris analysis focuses on the identification of a foreign ignitable liquid in debris collected from the scene of a suspected intentional fire.Chromatograms of the extracted debris are compared to a suitable reference collection containing chromatograms of unevaporated and evaporated ignitable liquids.However, there is no standardized
Thermometers Suspension feeding is one of the most widespread feeding strategies among benthic organisms.However, natural feeding ecology and energetics of benthic suspension feeders are poorly known.The scarcity of field methods, apparatus and protocols that facilitate obtention of reliable in situ data has contributed to this lack of knowledge.A
A pot experiment was conducted in order to examine the influence of soil contamination with diesel oil at 0.0, 2.4, 4.8 and 7.2 ml/kg on the activity of dehydrogenases, urease, acid phosphatase and alkaline phosphatase.The results indicated that diesel oil contamination of soil strongly inhibited the activity of dehydrogenases and soil Horse Cross